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. 2017 Nov 14;2017(11):CD009740. doi: 10.1002/14651858.CD009740.pub3

Summary of findings 5. (ITS) Safe intravenous systems compared to regular systems for preventing percutaneous exposure injuries caused by needles in healthcare personnel.

Safe intravenous systems compared to regular systems ITS for preventing percutaneous exposure injuries caused by needles in healthcare personnel
Patient or population: preventing percutaneous exposure injuries caused by needles in healthcare personnel
 Setting: healthcare
 Intervention: Safe intravenous systems
 Comparison: regular systems ITS
Outcomes Impact № of participants
 (studies) Quality of the evidence
 (GRADE)
Number of reported sharps injuries, level Study 1: effect size ‐5.20; confidence interval ‐7.98 to ‐2.42. Study 2: effect size ‐1.78; confidence interval ‐3.09 to ‐0.47. (2 observational studies) ⊕⊝⊝⊝
 VERY LOW 1 2 3
Number of reported sharps injuries, slope Study 1: Effect size ‐7.86; confidence interval ‐9.13 to ‐6.59. Study 2: Effect size 0.35; confidence interval ‐0.20 to 0.90. (2 observational studies) ⊕⊝⊝⊝
 VERY LOW 1 3 4
Interpretation of effect size: small (0‐0.2) medium (0.2‐0.5) large (0.6 and above), a effect size with negative sign implies decrease and positive sign implies increase of effect.
GRADE Working Group grades of evidenceHigh quality: We are very confident that the true effect lies close to that of the estimate of the effect
 Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
 Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
 Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

1 We downgraded the quality of evidence by one level due to risk of bias caused by lacking intervention fidelity (in the second study conventional devices were used during intervention period).
 2 We downgraded the quality of evidence by one level due to heterogeneity (I² = 79%).
 3 We downgraded the quality of evidence by one level due to imprecision (wide confidence interval).
 4 We downgraded the quality of evidence by two levels due to heterogeneity (I² = 99%).