Rajamani 2007.

Study characteristics
Methods	Study design: prospective, randomised, double‐blind, controlled trial Intention‐to‐treat: Not stated Sample size calculation: Not stated Setting: single centre. India Follow up: 2 hours
Participants	N = 82 (60.9% male) Age: 3 months to 10 years
Interventions	Group 1: (n = 41) extraoral infraorbital nerve block with 2 ml of bupivacaine 0.25% was administered and intravenous saline solution instead of intravenous analgesia Group 2: (n = 41) saline solution was administered for nerve blockade, instead of bupivacaine, and intravenous fentanyl (2 µg/kg) was provided
Outcomes	Pain: measured by Children and Infants Postoperative Pain Scale score Supplemental analgesic requirements Length of analgesia Time to feed
Notes	Jadad score: 5
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	The author informed us by email that randomisation was by drawing lots from a box including folded papers with the 2 anaesthetic options being pre‐written
Allocation concealment (selection bias)	Low risk	The author informed us by email that randomisation was by drawing lots from a box including folded papers with the 2 anaesthetic options being pre‐written
Blinding of participants and personnel (performance bias) All outcomes	Low risk	"anaesthesiologist (blinded to the analgesic used) assessed the child’s airway reflexes, recovery from anaesthesia, respiratory and cardiovascular status and operative site bleeding"
Blinding of outcome assessment (detection bias) All outcomes	Low risk	"child was handed over to the mother, and was monitored by the recovery room nurse. The nurse was blinded to the analgesia used"
Incomplete outcome data (attrition bias) All outcomes	Low risk	No losses
Selective reporting (reporting bias)	Low risk	The report of the study was free of suggestion of selective outcome reporting
Other bias	High risk	Size: sample size less than 50 per treatment arm