Summary of findings for the main comparison. Orthodontic treatment for deep bite and retroclined upper front teeth in children.

Orthodontic intervention (without extraction) compared with extraction or no orthodontic intervention for treating deep bite and retroclined upper front teeth in children
Patient or population: children with deep bite and retroclined upper front teeth Settings: orthodontic clinic Intervention: orthodontic treatment Comparison: extraction or no treatment
Outcomes	Illustrative comparative risks* (95% CI)		Relative effect (95% CI)	Number of Participants (studies)	Quality of the evidence (GRADE)	Comments
	Assumed risk	Corresponding risk
	Extraction or no treatment	Orthodontic treatment
Dento‐occlusal results of treatment, measured with the PAR index	No data are available as no RCTs or CCTs have been conducted.
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval; RR: risk ratio; RCT: randomised controlled trial; CCT: controlled clinical trial
GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate.