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. 2018 Feb 1;2018(2):CD004879. doi: 10.1002/14651858.CD004879.pub5

Comparison 3. Live vaccine versus placebo or no intervention (RCTs by age group).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Influenza 7 10812 Risk Ratio (M‐H, Random, 95% CI) 0.24 [0.14, 0.41]
1.1 under 2 years 0 0 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
1.2 under 6 years 7 10752 Risk Ratio (M‐H, Random, 95% CI) 0.22 [0.12, 0.39]
1.3 over 6 years 1 60 Risk Ratio (M‐H, Random, 95% CI) 0.47 [0.23, 0.97]
2 Influenza‐like illness 8 188418 Risk Ratio (M‐H, Random, 95% CI) 0.67 [0.62, 0.72]
2.1 under 2 years 0 0 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
2.2 under 6 years 5 38646 Risk Ratio (M‐H, Random, 95% CI) 0.67 [0.57, 0.77]
2.3 over 6 years 8 149772 Risk Ratio (M‐H, Random, 95% CI) 0.67 [0.60, 0.74]