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. 2018 Feb 1;2018(2):CD004879. doi: 10.1002/14651858.CD004879.pub5

Comparison 8. Inactivated vaccines (cohort studies by age group).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Influenza 6 1873 Risk Ratio (M‐H, Random, 95% CI) 0.42 [0.25, 0.73]
1.1 under 2 years 3 314 Risk Ratio (M‐H, Random, 95% CI) 0.63 [0.27, 1.47]
1.2 under 6 years 1 180 Risk Ratio (M‐H, Random, 95% CI) 0.34 [0.13, 0.89]
1.3 over 6 years 2 1379 Risk Ratio (M‐H, Random, 95% CI) 0.36 [0.12, 1.11]
2 Influenza‐like illness 11 11935 Risk Ratio (M‐H, Random, 95% CI) 0.53 [0.42, 0.67]
2.1 under 2 years 1 23 Risk Ratio (M‐H, Random, 95% CI) 0.47 [0.23, 0.93]
2.2 under 6 years 5 7046 Risk Ratio (M‐H, Random, 95% CI) 0.74 [0.59, 0.93]
2.3 over 6 years 7 4866 Risk Ratio (M‐H, Random, 95% CI) 0.44 [0.29, 0.68]
3 Otitis media 1 119 Risk Ratio (M‐H, Random, 95% CI) 0.48 [0.22, 1.03]
3.1 Children aged 6 months to 5 years 1 119 Risk Ratio (M‐H, Random, 95% CI) 0.48 [0.22, 1.03]