4. Results of univariate meta‐regression analysis for cardiovascular mortality.

Explanatory variable (n trials)	Exp(slope)*	95% Confidence interval Univariate P value	Proportion of variation explained	Interpretation
Case mix (% MI patients) (n = 22)	RR = 1.003	0.994 to 1.011 P = 1.00	0%	No evidence that risk ratio is associated with case mix
Dose of exercise (number of weeks of exercise training x average number of sessions/week x average duration of session in min) (n = 18)	RR = 1.000	1.000 to 1.000 P = 1.00	0%	No evidence that risk ratio is associated with increased dose of exercise
Type of CR (exercise only vs comprehensive CR) (n = 21)	RR = 0.802	0.560 to 1.148 P = 0.99	0%	No evidence that risk ratio is associated with type of CR
Duration of follow‐up (months) (n = 21)	RR = 0 .994	0.988 to 1.000 P = 0.27	0%	No evidence that risk ratio is associated with duration of follow‐up
Year of publication (pre 1995 vs post 1995) (n = 24)	RR = 0.990	0.970 to 1.012 P = 0.99	0%	No evidence that risk ratio is associated with year of publication
Setting (centre vs home) (n = 24)	RR = 1.033	0.863 to 1.24 P = 0.98	0%	No evidence that risk ratio is associated with setting
Risk of bias (low risk in ≥ 5 items v < 5 items) (n = 24)	RR = 0.914	0.816 to 1.022 P = 1.00	0%	No evidence that risk ratio is associated with risk of bias
Study location (n = 24)	RR = 0.979	0.735 to 1.303 P = 1.00	0%	No evidence that risk ratio is associated with study location
Sample size (n = 24)	RR = 1.000	1.000 to 1.000 P = 0.92	0%	No evidence that risk ratio is associated with sample size

P‐values adjusted for multiple testing