Andersen 1981.

Methods	Study design: RCT Country: Denmark Dates patients recruited: NR Maximum follow up: 37 months Post MI randomised four weeks after discharge.
Participants	Inclusion criteria: < 66 yrs with 1st MI. Exclusion criteria: patients without motivation and patients with impairment of the motorial apparatus that excluded training. N Randomised: total: 75 intervention: 38; comparator: 37 Diagnosis (% of pts): post MI: 100% Age (mean ±SD): intervention: 52.2 ± 7.5; comparator: 55.6 ± 6.3 Percentage male: intervention: 100%; comparator: 100% Ethnicity: NR
Interventions	Intervention: aerobic activity e.g. running, cycling, skipping + weights for 1 hour x 2 weekly for 2 months, then x 1 week for 10 months. Then continue at home. Components: exercise. Setting: centre‐based initially, followed by home. Aerobic exercise: Modality: e.g. running, cycling, skipping. Length of session: 1 hour Frequency: twice a week for two months, and then weekly for 10 months. Intensity: initial load of 150kpm/min (24.5W). increased with 150kpm/min every 6 mins. Resistance training included? yes ‐ weights. Total duration: 12 months. Co‐interventions: none described Comparator: non‐trained group (although some patients trained on own initiative). Co‐interventions: none described.
Outcomes	Total & CHD mortality. Non fatal MI. Outcomes measured at 1, 13, 25, & 37 months post‐discharge.
Source of funding	NR
Conflicts of interest	NR
Notes	88 participants were randomised, but 13 failed to follow up. Therefore 75 took part in the study. Several participants in C trained on own initiative, but were analysed as intention to treat. Authors concluded that physical training after MI appears to reduce consequences and to improve PWC, but PWC declines once participant on their own Physcial training had no effect on period of convalescence or return to work, but age and previous occupation were of significance.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"random numbers".
Allocation concealment (selection bias)	Unclear risk	Allocation concealment not reported.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Blinding not described.
Incomplete outcome data (attrition bias) All outcomes	High risk	15% lost to follow‐up, no description of withdrawals or dropouts.
Selective reporting (reporting bias)	Low risk	All outcomes were reported at all time points.
Groups balanced at baseline	Low risk	No significant differences in “basic data” for training and control patients.
Intention‐to‐treat analysis conducted	Low risk	Yes.
Groups received same treatment (apart from the intervention)	Low risk	Intervention included exercise only.