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. 2016 Jan 5;2016(1):CD001800. doi: 10.1002/14651858.CD001800.pub3

Bengtsson 1983.

Methods Study design: Single centre RCT
Country: Sweden
Dates patients recruited: October 1973 to January 1975
Maximum follow up: 14 months
Participants Inclusion criteria: patients > 65 years with MI.
Exclusion criteria: Severe cardiac failure, PMI‐syndrome, aortic regurgitation, cerebral infarct hemiparesis, disease of hip, status post‐poliomyelitis, amputation of lower extremity, diabetes with retinopathy, hyper/hypo thyroidism, hyperparathyroidism, mental illness.
N Randomised: total: 87; intervention: 44; comparator: 43
Diagnosis (% of pts): AMI: 100%
Age (years ± SD): intervention: 55.3 ± 6.6; comparator: 57.1 ± 6.6
Percentage male: 85%
 Ethnicity: NR
Interventions Intervention: Physical training under the supervision of a specially trained physiotherapist attached to the cardiological unit. Exercises consisted of interval training of large muscle groups on a mechanically braked ergometer bicycle, calisthenics and jogging for 30 minutes twice weekly over a period of 3 months. The intensity of the exercises was graded individually on the basis of the findings at the exercise tolerance test, and a maximum heart rate at exercise was prescribed.
Components: exercise, counselling and social measures.
Setting: supervised at the cardiological unit.
Aerobic exercise:
Modality: ergometer cycling.
Length of session: 30 min.
Frequency: twice per week.
Intensity: 90% of the max heart rate at the exercise tolerance test.
Resistance training included? interval training of large muscle groups, callisthenics.
Total duration: 3 months.
Co‐interventions: Counselling was given, supplying practical information on avoiding weight gain, to stop smoking, to keep on with the physical exercise and to resume leisure activities as much as possible.
Comparator: conventional care.
Co‐interventions: none described.
Outcomes Total mortality, CHD mortality, non‐fatal MI up to average 14 months.
Source of funding NR
Conflicts of interest NR
Notes Most emphasis on social/ psychological aspects.
171 patients were randomised and at discharge the cardiologist decided whether the patient was fit to take part in the rehab programme ‐ 45 patients were excluded at this point. Seven of intervention group declined to take part, but six of these were seen at follow up and included in the analysis because "control group probably had a comparable number who would have declined further treatment."
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "allocated at random".
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Blinding not described.
Incomplete outcome data (attrition bias) 
 All outcomes High risk Description of withdrawals & dropouts: Intervention Group 29%;Control group 33% lost to follow up from 126 who took part. 171 were randomised and then 45 excluded by cardiologist.
Selective reporting (reporting bias) Low risk All outcomes were reported at all time points.
Groups balanced at baseline Low risk “No significant differences with regard to age, sex, number of infarcts, highest serum glutamic oxaloacetic transaminase value, heart size on X‐ray, or number of days in hospital existed between the two groups”.
Intention‐to‐treat analysis conducted Low risk Yes.
Groups received same treatment (apart from the intervention) High risk "The program comprised…. Physical training supervised by a physiotherapist; counselling, individually and in groups; counselling of members of the family; social measures”.