Comparison 2. Selective serotonin reuptake inhibitors (SSRI) versus tricyclic antidepressants (TCA).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Improvement in depression: HAM‐D score: continuous (follow‐up score)	1	14	Mean Difference (IV, Fixed, 95% CI)	‐3.20 [‐10.87, 4.47]
2 Improvement in depression: HAM‐D score: dichotomized (> 50% reduction)	2	64	Risk Ratio (M‐H, Random, 95% CI)	0.89 [0.54, 1.46]
3 Improvement in depression: CGI‐I (score of 1 or 2)	2	64	Risk Ratio (M‐H, Fixed, 95% CI)	1.24 [0.68, 2.24]
4 Study dropouts	2	64	Risk Ratio (M‐H, Fixed, 95% CI)	0.81 [0.51, 1.30]
5 Adverse effects	1	14	Risk Ratio (M‐H, Fixed, 95% CI)	1.05 [0.67, 1.64]