2. Risk of bias in included studies.
Study design | High risk | Low risk | Unclear risk | Total |
Case‐control | 3 | 2 | 18 | 23 |
Cohort | 14 | 8 | 18 | 40 |
RCT/CCT | 7 | 12 | 55 | 74 |
Total | 24 | 22 | 91 | 137 |
CCT: controlled clinical trial RCT: randomised controlled trial
This table displays the overall methodological quality assessment of the included studies described in the text and represented in extended form (with all items of the tools) in Figure 1.