Comparison 9. Serious adverse events: demyelinating diseases (multiple sclerosis, optic neuritis) ‐ cohort studies.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Influenza vaccination (seasonal) ‐ demyelinating diseases (unadjusted data)	1	223898	Odds Ratio (M‐H, Random, 95% CI)	0.16 [0.02, 1.25]
1.1 General population	0	0	Odds Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.2 Pregnant women	1	223898	Odds Ratio (M‐H, Random, 95% CI)	0.16 [0.02, 1.25]
2 Influenza vaccination (H1N1) ‐ demyelinating diseases (unadjusted)	1	144252	Risk Ratio (M‐H, Random, 95% CI)	2.06 [0.51, 8.22]