pba Benowitz 2010.
Methods | Case‐control study assessing the effectiveness of influenza vaccination of pregnant women in preventing hospitalisation for influenza in their newborns. Study period ranged from October 2000 to April 2009. | |
Participants | Cases (n = 113): infants below 12 months hospitalised for influenza between October 2000 and April 2009 who tested positive for influenza with direct fluorescent antibody (DFA) Controls (n = 192): participants hospitalised for influenza during the same time interval as the cases but negative with the DFA test. For each case 1 or 2 controls matched for birth date and date of hospitalisation were randomly selected. |
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Interventions | Immunisation with influenza vaccine during pregnancy (until 14 days before delivery) | |
Outcomes | DFA‐confirmed influenza | |
Notes | This study was supported by the National Center for Research Resources, a component of the National Institutes of Health. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
CC ‐ case selection All outcomes | Low risk | Infants hospitalised with DFA positive |
CC ‐ control selection All outcomes | Low risk | Infant hospitalised with DFA negative |
CC ‐ comparability All outcomes | Low risk | Matching |
CC ‐ exposure All outcomes | Unclear risk | Structured interview |
Summary assessment | Unclear risk | Unclear |