2. Conversion factors for alcohol consumption and efficacy scores of trials.

Trial	Reported units	Conversion factor	Source of conversion	Efficacy score	Treatment exposure1
Aalto 2000	g/week	1	NA	10.5	45, 105
Altisent 1997	Units/week	8	Altisent 1997	8.5	20
Babor 2006	Drinks/week	14	Babor 2006	11	4
Bazargan‐Hejazi 2005	Alcohol consumption	NR	NA	9	17.5
Beckham 2007	Drinks/day	11.671 x 7	Miller 1991	4.5	52.5
Beich 2007	Drinks/week	12	Beich 2007	11	10
Bernstein 2010	Drinks/week	11.671	Miller 1991	6.5	32.5
Bischof 2008	g/day	7	NA	6.5	60
Blow 2006	Drinks/week	13	Blow 2009*	7.5	7.5
Cherpitel 2009	Drinks/week	11.671	Miller 1991	9	17.5
Córdoba 1998	Units/week	8	Córdoba 1998	11	15
Crawford 2004	Units/week	8	Miller 1991	10.5	30
Crawford 2010	Alcohol consumption	NR	NA	8.5	30
Curry 2003	Drinks/week	11.671	Miller 1991	8.5	22.5
D'Amico 2008	Basic statistics	NR	NA	7.5	25
D'Onofrio 2008	Drinks/week	11.671	Miller 1991	10.5	6.7
D'Onofrio 2012	Drinks/week	11.671	Miller 1991	10.5	7;17
Daeppen 2007	Drinks/week	10	Daeppen 2007	7	15
Dent 2008	Alcohol consumption	NR	NA	11.5	5; 45
Désy 2010	Drinks/week	11.671	Miller 1991	10.5	7.5
Díez 2002	Units/week	8	Díez 2002	10.5	10
Drummond 2009	Drinks previous 180 days	8 x (7/180)	Drummond 2009	10.5	40; 200
Drummond 2014	Drinks/day	8 x 7	Drummond 2009	8	26
Ettner 2014	Drinks/week	11.671	Miller 1991	11	108
Fernández 1997	Units/week	10	Miller 1991	7.5	10
Field 2010	Drinks/week	11.671	Miller 1991	7.5	17.5
Fleming 1997	Drinks/week	12	Fleming 1997	10.5	40
Fleming 1999	Drinks/week	12	Fleming 1999	9	40
Fleming 2004	Drinks/month	11.671 x (12/52)	Miller 1991	4.5	40
Fleming 2010	Drinks in previous 28 days	11.671 x (7/28)	Miller 1991	8.5	42.5
Heather 1987	Units/month	8 x (12/52)	Heather 1987	8.5	7.5
Helstrom 2014	Drinks/day	11.671 x 7	Miller 1991	7	37.5
Huas 2002	Units/week	10	Heather 2006	10	7.5
Israel 1996	Drinks/month	13.456 x (7/28)	Miller 1991	7.5	150
Kaner 2013	Drinks/day	8 x 7	Kaner 2013	11	26
Kunz 2004	Drinks/week	11.671	Miller 1991	6	37.5
L'Engle 2014	Alcohol consumption	NR	NA	8	180
Lane 2008	Alcohol consumption	NR	NA	10.5	7.5
Lock 2006	Drinks/week	8	Miller 1991	12	7.5
Longabaugh 2001	Alcohol consumption	NR	NA	6	50
Maisto 2001	Drinks/month	17.01 x (7/30)	Miller 1991	5	13.5; 65
McDevitt‐Murphy 2014	Drinks/week	11.671	Miller 1991	5.5	60
McIntosh 1997	Drinks/month	13.456 x (12/52)	Miller 1991	10.5	60
Mello 2008	Alcohol consumption	NR	NA	7	45
Mertens 2014	Alcohol consumption	NR	NA	7.5	10
Monti 2007	Drinks/week	11.671	Miller 1991	7.5	85
Moore 2011	Standard drinks/week	11.671	Miller 1991	9.5	83
Noknoy 2010	Drinks/week	10	Furtwaengler 2013	11	45
Ockene 1999	Drinks/week	12.8	Ockene 1999	10	7.5
Richmond 1995	Drinks/week	10	Richmond 1995	9.5	5, 57.5
Rodríguez 2003	Alcohol consumption	NR	NA	10.5	17.5
Romelsjö 1989	g/day	1 x 7	NA	4.5	7.5
Rubio 2010	Drinks/week	12.8	Rubio 2010	9.5	32.5
Schaus 2009	Drinks/week	11.671	Miller 1991	8	40
Scott 1990	Units/week	8	Miller 1991	11	10
Segatto 2011	Alcohol consumption	NR	NA	6	45
Senft 1997	Drinks/3 months	11.671 x (4/52)	Miller 1991	9	16
Seppa 1992	Alcohol consumption	NR	NA	8.5	15
Soderstrom 2007	Drinks/last 90 days	11.671 x (7/90)	Miller 1991	6.5	32.5
Sommers 2006	Alcohol consumption	NR	NA	7	40
Sommers 2013	Drinks/week	11.671	Miller 1991	7.5	40
Spirito 2004	Standard drinks/month	11.671 x (12/52)	Miller 1991	7	40
Spirito 2011	Alcohol consumption	NR	NA	7.5	52.5
Tait 2004	alcohol consumption	NR	NA	8	37.5
Tomson 1998	g/week	1	NA	8.5	37.5
Wallace 1988	Units/week	8	Miller 1991	9.5	7.5
Walton 2010	Alcohol consumption	NR	NA	7	37
Watson 2013	Drinks/week	8	Watson 2013	9.5	20
Woolard 2013	Alcohol consumption	NR	NA	5.5	72.5

* Blow 2009 is a report of Blow 2006.
 ¹ Treatment exposure was calculated in minutes. Where two values appear, these are the durations of different intervention arms.

Abbreviations: NA: not applicable; NR: not reported.