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. 2018 Feb 11;2018(2):CD001487. doi: 10.1002/14651858.CD001487.pub3

Eickhoff 1987.

Methods Site: Femoral to BK popliteal
Study design: multicentre RCT
Method of randomisation: sealed envelopes
Blinding: unblinded, intention to treat
Exclusions post randomisation: none
Losses to follow up: none
Participants Country: Scandinavia
Setting: hospital
No. of participants: 105 (55 PTFE, 50 HUV)
Age: 68 yrs
Sex: 60 male, 45 female
Inclusion criteria: DM 12, critical ischaemia 80. BK fem‐pop for short distance IC or critical ischaemia, if no vein or CABG intended
Exclusion criteria: short life expectancy, previous graft, Buerger's, coagulopathy
Interventions PTFE versus HUV (diameter at discretion of operating surgeon)
Outcomes Secondary patency
Notes Post‐op anti‐thrombotic/coagulant therapy unknown
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Unclear as to how the randomisation sequence was generated
Allocation concealment (selection bias) Low risk Sealed envelopes used
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Operative blinding impossible in this type of trial
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Outcome assessors and patients not obviously blinded
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No losses, clear life table data
Selective reporting (reporting bias) Low risk All stated outcomes reported
Other bias Unclear risk Anticoagulation protocol not stated