Comparison 1. Ergometrine‐oxytocin versus oxytocin (any dose).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Blood loss = or > 500 ml	6	9332	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.82 [0.71, 0.95]
2 Blood loss = or > 1000 ml	5	7954	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.78 [0.58, 1.03]
3 Manual removal of the placenta	6	9332	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.03 [0.80, 1.33]
4 Blood transfusion	4	7482	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.37 [0.89, 2.10]
5 Elevation diastolic blood pressure	4	7486	Peto Odds Ratio (Peto, Fixed, 95% CI)	2.40 [1.58, 3.64]
6 Vomiting	3	5458	Peto Odds Ratio (Peto, Fixed, 95% CI)	4.92 [4.03, 6.00]
7 Nausea	3	5458	Peto Odds Ratio (Peto, Fixed, 95% CI)	4.07 [3.43, 4.84]
8 Vomiting + nausea combined	4	7486	Peto Odds Ratio (Peto, Fixed, 95% CI)	5.71 [4.97, 6.57]
9 Therapeutic oxytocics	3	5465	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.83 [0.72, 0.96]
10 3rd stage > 30 minutes	5	7304	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.07 [0.78, 1.48]
11 3rd stage > 60 minutes	2	4861	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.11 [0.68, 1.81]
12 Apgar score = or < 6 at 5 minutes	2	5468	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.00 [0.67, 1.50]
13 Jaundice	2	5468	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.97 [0.84, 1.12]
14 Not breastfed at discharge	1	3440	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.10 [0.90, 1.33]
15 Admission to neonatal intensive care unit	1	3440	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.04 [0.88, 1.24]