Table 3:
Top 10 significantly perturbed (enhanced) KEGG Signaling and Metabolism pathways following miR-181a/b-1 over-expression at day 7 of osteogenic induction.
| Pathway | Mean Linear FC |
P-Value |
|---|---|---|
| Oxidative phosphorylation (hsa00190) | 24.69 | 4.17e-06 |
| Ribosome (hsa0310) | 19.84 | 1.35e-05 |
| Spliceosome (hsa03040) | 6.46 | 3.89e-03 |
| Purine metabolism (hsa00230) | 5.09 | 9.91e-03 |
| Proteasome (hsa03050) | 4.81 | 1.39e-02 |
| Pyrimidine metabolism (hsa00240) | 4.32 | 1.82e-02 |
| Protein processing in endoplasmic reticulum (hsa04141) | 3.77 | 2.84e-02 |
| Protein export (hsa03060) | 3.74 | 4.66e-02 |
| Glutathione metabolism (hsa00480) | 3.23 | 4.84e-02 |
| Mineral absorption (hsa04978) | 2.83 | 6.89e-02 |