Comparison 7. Intranasal midazolam versus intravenous diazepam.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Seizure Cessation	2	122	Risk Ratio (M‐H, Fixed, 95% CI)	0.98 [0.91, 1.06]
2 Time from drug administration to stopping of seizures [minutes]	3		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
2.1 Treatment initiation time (minutes)	1	52	Mean Difference (IV, Fixed, 95% CI)	‐2.0 [‐3.03, ‐0.97]
2.2 Time for drug effect (minutes)	2	122	Mean Difference (IV, Fixed, 95% CI)	0.62 [‐0.14, 1.38]
2.3 Total time to seizure cessation (minutes)	2	112	Mean Difference (IV, Fixed, 95% CI)	0.80 [0.24, 1.35]