Table 1.
Number of participants with most often occurring serious adverse events during treatment
Trial | Gastrointestinal haemorrhage | Hepatorenal syndrome (with or without hepatic failure) | Septicaemia | Hepatocellular carcinoma | ||||
Prednisolone | Placebo | Prednisolone | Placebo | Prednisolone | Placebo | Prednisolone | Placebo | |
Helman 1971 | 3 | |||||||
Porter 1971 | 4 | 2 | ||||||
Campra 1973 | 3 | 5 | 4 | |||||
Blitzer 1977 | 3 | 2 | 2 | 2 fungal | 1 | |||
Mendenhall 1977 | Not reported | |||||||
Maddrey 1978 | 1 | 1 | 3 | 6 | ||||
Shumaker 1978 | 3 | 3 | 2 | |||||
Depew 1980 | 2 | 1 | 2 | 1 | ||||
Theodossi 1982 | 11 | 6 | 7 | 6 | ||||
Bories 1987 | 3 | 3 | 2 | |||||
Carithers 1989 | 2 | 4 | 1 | |||||
Mendenhall 1984 | 2 | |||||||
Ramond 1992 | 1 | 2 | 1 | 1 | ||||
De 2014 | 2 | 3 | 3 | 3 | 1 |