| Study | Reason for exclusion |
|---|---|
| Alvarez 2004 | An observational study (patient series). Thirteen participants with severe alcoholic hepatitis were treated with systemic glucocorticosteroids and total enteral nutrition. |
| Cabré 2000 | A randomised trial of glucocorticosteroids versus nutrition in people with alcoholic hepatitis. Participants received oral or intravenous prednisolone or enteral nutrition (2000 kcal/d of a chemically defined polymeric enteral diet enriched in branched‐chain amino acids) |
| Christensen 1981 | A quasi‐randomised clinical study |
| Copenhagen 1969 | A meta‐analysis |
| Daures 1991 | A meta‐analysis |
| Dhanda 2016 | A prospective single‐ centre cohort of patients with severe alcoholic hepatitis treated with steroids ‐ the incidence and significance of infection |
| Galambos 1984 | Reported in article through private contacts as part of Shumaker 1978 |
| Gill 1984 | The trial randomised 10 patients with severe alcoholic hepatitis to prednisolone, testosterone, and amino acid supplement versus no intervention. |
| Goldis 2000 | An observational study (patient series); the authors used a control group from the same centre. |
| Hozo 1996 | The trial randomised patients with alcoholic liver cirrhosis to glucocorticosteroids versus placebo. |
| Imperiale 1990 | A meta‐analysis |
| Lesesne 1978 | A randomised trial of glucocorticosteroids versus nutrition in patients with alcoholic hepatitis. Participants received glucocorticosteroids plus permission to eat as they wanted or a maximum of 600 kcal/d as intravenous glucose, while the control group received caloric supplements of at least 1600 kcal/d |
| Mal 1991 | Abstract about influence of corticosteroids on the level of serum TNF concentrations |
| Mendenhall 1993 | A chapter on alcoholic hepatitis in a book |
| Moreno 2014 | A multi central study with two groups of comparison of intensive enteral nutrition with complete nutrition, in both groups receiving prednisolone |
| Morris 2005 | An observational study (patient series) |
| Naganuma 2014 | The trial of granulocytapheresis and leukocytapheresis for the treatment of severe alcoholic hepatitis |
| Naveau 2004 | The trial randomised patients with alcoholic hepatitis to receive infliximab versus placebo. All participants received prednisone too |
| Phillips 2001 | The trial randomised participants to antioxidants versus glucocorticosteroids |
| Poynard 1991 | A meta‐analysis on alcoholic hepatitis |
| Reynolds 1989 | A narrative review on alcoholic hepatitis |
| Schlichting 1976 | A quasi‐randomised clinical study |
| Spahr 2002 | The trial randomised patients with alcoholic hepatitis to receive infliximab versus placebo. All participants received prednisone too |
| Stewart 2002 | The trial stratified participants by gender and glucocorticosteroid use, and then randomised participants to receive antioxidants versus placebo |
| Tygstrup 1979 | A meta‐analysis |
| Young‐Sun Lee | A review |
TNF: tumour necrosis factor