5. Construct Validity.
| Study ID | Index | Comparison | Correlation |
| Burger 2011 | Baron Score | SCCAI | ƙ = 0.27 |
| Truelove and Richards Index | ƙ = 0.58 | ||
| Dhanda 2012 | Mayo Clinic Endoscopic Subscore | Riley Score | Week 4 r = 0.55 |
| Higgins 2005a | St. Mark's Index | UCDAI | r = 0.881 (95% CI 0.814‐0.925); ρ = 0.867 |
| SCCAI | r = 0.908 (95% CI 0.855‐0.924); ρ = 0.866 | ||
| Seo Index | r = 0.803 (95% CI 0.699‐0.873); ρ = 0.705 | ||
| Hirai 2010 | Baron Score | Rachmilewitz Score | Week 0 r = 0.39 (95% CI 0.18‐0.57, P = 0.0004) Week 4 r = 0.56 (95% CI 0.36‐0.71, P < 0.0001) Week 8 r = 0.76 (95% CI 0.60‐0.85, P < 0.0001) |
| UCDAI | Week 0 r = 0.49 (95% CI 0.29‐0.64, P < 0.0001) Week 4 r = 0.72 (95% CI 0.57‐0.82, P < 0.0001) Week 8 r = 0.85 (95% CI 0.74‐0.91, P < 0.0001) |
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| Seo Index | Week 0 r = 0.29 (95% CI 0.06‐0.49, P = 0.01) Week 2 r = 0.29 (95% CI 0.04‐0.51, P = 0.02) Week 4 r = 0.53 (95% CI 0.29‐0.70, P < 0.0001) |
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| Lichtiger Index | Week 0 r = 0.47 (95% CI 0.26‐0.62, P < 0.0001) Week 4 r = 0.56 (95% CI 0.35‐0.71, P < 0.0001) Week 8 r = 0.78 (95% CI 0.64‐0.78, P < 0.0001) |
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| Rachmilewitz Endoscopic Score | Rachmilewitz Score | Week 0 r = 0.34 (95% CI 0.11‐0.52, P = 0.0003) Week 2 r = 0.66 (95% CI 0.48‐0.78, P < 0.0001) Week 4 r = 0.89 (95% CI 0.73‐0.71, P < 0.0001) |
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| UCDAI | Week 0 r = 0.44 (95% CI 0.23‐0.60, P < 0.0001) Week 4 r = 0.79 (95% CI 0.67‐0.87, P < 0.0001) Week 8 r = 0.89 (95% CI 0.82‐0.94, P < 0.0001) |
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| Lichtiger Index | Week 0 r = 0.35 (95% CI 0.13‐0.54, P =0.002) Week 4 r = 0.28 (95% CI 0.02‐0.49, P = 0.003) Week 8 r = 0.65 (95% CI 0.44 to 0.78, P < 0.0001) |
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| Seo Index | Week 0 r = 0.33 (95% CI 0.10‐0.51, P = 0.005) Week 4 r = 0.67 (95% CI 0.50‐0.79, P < 0.0001) Week 8 r = 0.80 (95% CI 0.67‐0.88, P < 0.0001) |
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| Jun 2008 | CGSUC | Truelove and Witts Score | ρ = 0.750 (P < 0.001) |
| Baron Score | ρ = 0.740 (P < 0.001) | ||
| Modified Baron Score | ρ = 0.742 (P < 0.001) | ||
| Jeroen Score | ρ = 0.799 (P < 0.001) | ||
| Azzolini Score | ρ = 0.685 (P < 0.001) | ||
| Truelove and Witts Score | CGSUC | ρ = 0.750 (P < 0.001) | |
| Baron Score | ρ = 0.814 (P < 0.001) | ||
| Modified Baron Score | ρ = 0.760 (P < 0.001) | ||
| Jeroen Score | ρ = 0.782 (P < 0.001) | ||
| Azzolini Score | ρ = 0.756 (P < 0.001) | ||
| Baron Score | CGSUC | ρ = 0.740 (P < 0.001) | |
| Truelove and Witts Score | ρ = 0.814 (P < 0.001) | ||
| Modified Baron Score | ρ = 0.750 (P < 0.001) | ||
| Jeroen Score | ρ = 0.828 (P < 0.001) | ||
| Azzolini Score | ρ = 0.732 (P < 0.001) | ||
| Modified Baron Score | CGSUC | ρ = 0.742 (P < 0.001) | |
| Baron Score | ρ = 0.760 (P < 0.001) | ||
| Truelove and Witts Score | ρ = 0.750 (P < 0.001) | ||
| Jeroen Score | ρ = 0.761 (P < 0.001) | ||
| Azzolini Score | ρ = 0.693 (P < 0.001) | ||
| Jeroen Score | CGSUC | ρ = 0.799 (P < 0.001) | |
| Baron Score | ρ = 0.782 (P < 0.001) | ||
| Truelove and Witts Score | ρ = 0.828 (P < 0.001) | ||
| Modified Baron Score | ρ = 0.761 (P < 0.001) | ||
| Azzolini Score | ρ = 0.788 (P < 0.001) | ||
| Azzolini Score | CGSUC | ρ = 0.685 (P < 0.001) | |
| Truelove and Witts Score | ρ = 0.756 (P < 0.001) | ||
| Baron Score | ρ = 0.732 (P < 0.001) | ||
| Modified Baron Score | ρ = 0.693 (P < 0.001) | ||
| Jeroen Score | ρ = 0.788 (P < 0.001) | ||
| Naganuma 2010 | EAI | Lichtiger Index | r = 0.77 (P < 0.001) |
| Matts Score | r = 0.91 (P < 0.001) | ||
| Rachmilewitz Endoscopic Score | r = 0.87, (P < 0.001) | ||
| Nishio 2006 | Magnifying Colonoscopy Grade | Riley Score | ρ = NS (P < 0.001) |
| Rubin 2012 | Mayo Clinic Endoscopic Subscore | SCCAI | r = 0.525 (P < 0.0001) |
| Rubin Histologic Score | r = 0.597 (P < 0.0001) | ||
| Samuel 2013 | UCCIS | SCCAI | r = 0.62 (P < 0.0001) |
| Rachmilewitz Score | r = 0.5 (P < 0.001) | ||
| Patient‐Defined Remission Score | r = 0.43 (P < 0.01) | ||
| Schoepfer 2009 | Rachmilewitz Score (endoscopic) | Rachmilwitz Score (clinical) | r = 0.672 (P < 0.01) |
| Thomas 2009 | Baron Score | Truelove and Richards Score | ƙ = 0.58 |
| SCCAI | ƙ = 0.27 | ||
| Travis 2013 | UCEIS | Visual Analogue Scale | median 0.93 across investigators (minimum 0.78, maximum 0.99) statistically significant P > 0.05 |
| Walsh 2009 | Baron Score | Modified Baron Score | ƙ = 0.89 |
| Baron Score | Mayo Endoscopic Subscore | ƙ = 0.83 |
ρ = Spearman's rank correlation coefficient
Abbreviations: CGSUC, Chinese Grading Score for Ulcerative Colitis; EAI, Endoscopic Activity Index; IL, Interleukin; NS, Not Stated; SCCAI, Simple Clinical Colitis Activity Index