Dhanda 2012.

Methods	Post‐hoc analysis of data from a multicenter randomised controlled trial in steroid‐refractory moderate to severe UC (NCT00430898) (N = 149)
Data	Clinical and endoscopic assessment of disease activity was performed at baseline, week 4, week 8 Histologic assessed of disease activity was performed as an optional sub study Biopsies were scored by a single blinded pathologist
Comparisons	Riley Score (histopathology)
Outcomes	Construct validity (see Table 5)
Notes	Endoscopic scoring index evaluated: Mayo Clinic Endoscopic Subscore Correlation was measured using Spearman's rho Correlation estimate for endoscopic and histologic measures only reported at week 4
Risk of bias
Item	Authors' judgement	Description
Blinding?	Unclear	It is unclear whether the endoscopist was blinded to clinical information
Independent Observation?	Unclear	Not relevant (construct validity)