Schoepfer 2009.

Methods	115 UC patients requiring colonoscopy were prospectively enrolled The clinical and endoscopic portions of the Rachmilewitz Endoscopic Score were assessed Fecal and blood samples were obtained after colonoscopy 4 trained gastroenterologists graded the endoscopic findings
Data	19 patients underwent 2 colonoscopies, therefore there were 134 colonoscopies performed
Comparisons	Rachmilewitz Score (clinical) Fecal calprotectin C‐reactive protein Blood leukocytes
Outcomes	Criterion validity, construct validity (see Table 4 and Table 5)
Notes	Endoscopic scoring index assessed: Rachmilewitz Endoscopic Score
Risk of bias
Item	Authors' judgement	Description
Blinding?	Yes	All gastroenterologists performing the colonoscopies were unaware of clinical and biomarker data to avoid bias The clinical score was performed by a different physician than the one that performed the colonoscopy
Independent Observation?	Unclear	Not adequately described (not necessary for construct and criterion validation)