Study	Reason for exclusion
Chen 2011	Only abstract available (report is of published conference proceedings). Contacted authors but no reply. Insufficient information available to fully assess trial for either qualitative or quantitative inclusion.
Chen 2012	Only abstract available (report is of published conference proceedings). Contacted authors but no reply. Insufficient information available to fully assess trial for either qualitative or quantitative inclusion.
Czyz 2011	Not a randomised controlled trial
Eljamel 2008	The addition of repetitive photodynamic therapy essentially precludes analysis of this trial as a test of intraoperative imaging alone.
Koc 2008	Prospective study; participants were not randomised.
Rohde 2011	This trial assessed specificity and sensitivity of intraoperative 3D ultrasound as diagnostic test rather than treatment option.
Seddighi 2016	Only abstract available (report is of published conference proceedings). Contacted authors but no reply. Insufficient information available to fully assess trial for either qualitative or quantitative inclusion.
Stepp 2007	Further report of Stummer 2006 trial; only new data are on spectroscopy and photodynamic therapy.
Stummer 2017	A randomised controlled trial on the diagnostic effects of different doses of 5‐aminolevulinic acid (clinical, spectrophotometric, pathological).
Wu 2003	Author stated that this was not a randomised controlled trial.
Wu 2004	Author stated that this was not a randomised controlled trial.
Wu 2007	Author stated that this was not a randomised controlled trial.
Zhang 2015	Not a randomised controlled trial; "patient selection was based on economic status and the availability of iMRI'"

iMRI: intraoperative magnetic resonance imaging