NCT02040272.

Trial name or title	A study to determine if it is feasible to recruit into a randomised trial comparing (extended) pleurectomy decortication versus no pleurectomy decortication in patients with malignant pleural mesothelioma
Methods	Phase III
Participants	Participants with histologically confirmed mesothelioma and disease confined to one hemithorax
Interventions	Experimental arm: chemotherapy plus (Extended) pleurectomy decortication Standard arm: chemotherapy only
Outcomes	Primary Outcome Measures 1. Ability to randomise 50 patients (TimeFrame: 24 months) 2. Ability to randomise 50 patients within the first 24 months or the ability to recruit 25 patients within any 6 month period Secondary Outcome Measures 1. Survival from the time point of randomisation (time frame: follow‐up for up to 5 years) 2. health‐related quality of life as assessed using QLQ 30 and LC‐13 scales (time frame: follow‐up for up to 5 years)
Starting date	May 2015
Contact information	Eric Lim: e.lim@rbht.nhs.uk
Notes	Sponsor: Royal Brompton & Harefield NHS Foundation Trust