Study	Reason for exclusion
Bao 2007	Allocation: randomised. Participants: people with schizophrenia and agitation. Intervention: oral aripiprazole + clonazepam versus oral clozapine.
Chen 2009	Allocation: randomised. Participants: schizophrenia, displaying acute agitation. Intervention: oral aripiprazole versus oral olanzapine.
Cutler 2006	Allocation: randomised. Participants: schizophrenia acute relapse, not displaying aggression or agitation.
Fleischhacker 2009	Allocation: randomised. Participants: schizophrenia acute relapse, not displaying acute aggression or agitation.
Kane 2002	Allocation: double‐blind randomised. Participants: schizophrenia and schizoaffective disorders, not displaying acute aggression or agitation.
Kinon 2008	Allocation: randomised. Participants: people with schizophrenia experiencing acute agitation. Intervention: oral aripiprazole 15 mg versus oral olanzapine 20 mg.
Li 2009	Allocation: randomised. Participants: people with schizophrenia, displaying acute aggression or agitation. Intervention: oral aripiprazole versus oral aripiprazole + valproate slow‐release tablet.
Liang 2005	Allocation: randomised. Participants: schizophrenia acute disorder, not displaying acute aggression or agitation.
Liu 2012	Allocation: randomised. Participants: schizophrenia, displaying acute aggression or agitation. Intervention: oral aripiprazole vs oral aripiprazole + magnesium valproate.
McEvoy 2007	Allocation: randomised. Participants: schizophrenia spectrum acute exacerbation, not displaying acute aggression or agitation.
NCT01469039	Allocation: randomised. Participants: schizophrenia, not displaying acute aggression or agitation (except for one sub‐study). Intervention: IM aripiprazole lauroxil long acting 441 mg vs IM aripiprazole lauroxil long acting 882 mg vs IM placebo.
Potkin 2003	Allocation: randomised. Participants: schizophrenia and schizoaffective disorder, not displaying acute aggression or agitation.
Simpson 2010	Allocation: randomised. Participants: adults patients acutely agitated attending psychiatric clinic. Intervention: oral quetiapine 300 mg vs IM haloperidol 5 mg + lorazepam 2 mg + benztropine mesylate 2 mg.
Tandon 2006	Allocation: randomised. Participants: schizophrenia and schizoaffective disorder, not displaying acute aggression or agitation.
Wang 2014	Allocation: randomised. Participants: schizophrenia, displaying acute aggression and agitation. Intervention: aripiprazole + quetiapine vs aripiprazole + olanzapine vs quetiapine + olanzapine.
Xie 2011	Allocation: randomised. Participants: schizophrenia, displaying acute aggression and agitation. Intervention: oral aripiprazole versus oral aripiprazole + magnesium valproate.

IM: intramuscular.