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. 2019 Apr 3;42:225–237. doi: 10.1016/j.ebiom.2019.03.040

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Effects of JWH133 on evoked EPSCs and IPSCs in VTA DA neurons. (a) Representative typical traces of paired-pulse (50 ms interval) stimulation-induced eEPSCs before (left trace pair) and after (right trace pair) exposure to JWH133. Bar graph illustrating that JWH133 (10 μM) altered neither eEPSC amplitude (b) nor P2/P1 ratio (c) in 10 VTA slices tested. (d) Representative typical traces of paired-pulse (50 ms interval) stimulation-induced eIPSCs before (left trace pair) and after (right trace pair) exposure to JWH133. Bar graph illustrating that JWH133 (10 μM) did not change eIPSC amplitude (e) and P2/P1 ratio (f) in 10 VTA slices tested.