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. 2019 Apr 30;9:6720. doi: 10.1038/s41598-019-43180-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Simulation Initialization and Graphical Output. Control panel for the optic nerve modelling parameters (top right section: “Model”) and superoxide diffusion parameters (middle right section: “Diffusion and Scavenging rates”). The platform allows recording a simulation as well as taking snapshots at different time intervals. It also displays the number of iterations performed, the proportion of alive axons, total amount of superoxide in moles as well as the elapsed simulation time. A schematic of the initial state for optic nerve axons is depicted in green.