Table 3.
Correlation of CSF α-dicarbonyl and AGE levels with MS disease parameters.
| Correlations (R2) | |||
|---|---|---|---|
| EDSS | Number of relapses | Disease duration, years | |
| MGO | −0.175 | −0.023 | −0.153 |
| GO | −0.378 | 0.213 | 0.008 |
| 3-DG | −0.242 | −0.062 | 0.082 |
| Free CML | 0.125 | −0.209 | −0.357 |
| Free CEL | −0.32 | −0.134 | −0.165 |
| Free MG-H1 | 0.284 | 0.014 | −0.542* |
| PB CML | −0.18 | 0.377 | −0.152 |
| PB CEL | −0.099 | 0.306 | −0.452 |
| PB MG-H1 | −0.551* | 0.029 | −0.12 |
*
p < 0.05. Correlation is determined between MGO, GO, and 3DG, protein-bound (PB) CML, CEL, and MG-H1, and free CML, CEL, and MG-H1 in the CSF with EDSS, number of relapses and disease duration. Data is analyzed using partial correlation analysis and corrected for age, gender, medication use, and [glucose]CSF.