Table 1.
Demographics for subjects included in the analysis
| Demographic | p Value | Gene negative | Gene carriers | FTD |
|---|---|---|---|---|
| Age, y (SD) | <0.00001 | 47.8 (15.5) | 44.5 (12.3) | 62.4 (8.6) |
| Sex (M/F) | nsa | 49(61%)/31(39%) | 40(59%)/28(41%) | 7(29%)/17(71%) |
| Hand (L/R/Ambi) | ns | 74(93%)/5(6%)/1 (1%) | 58(85%)/8(12%)/2 (3%) | 22(92%)/2(8%)/0 (0%) |
| Education, y (SD) | ns | 13.7 (3.5) | 13.8 (3.2) | 12.2 (4.5) |
For parametric data, analysis of variance was used and we report the mean, and the standard deviation in parentheses.
For categorical data, the χ2 test was used and we report the numbers in each category.
As expected, people with FTD were older than both gene carriers (p < 0.00001) and gene-negative subjects (p < 0.00001).
Key: FTD, frontotemporal dementia; ns, non-significant >0.1; SD, standard deviation.
a
Although sex differences were not significant when tested across all three groups, pairwise tests confirmed that there were fewer men in the FTD patient group compared with both the gene carrier (p = 0.02) and gene-negative (p = 0.01) groups.