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. 2019 Apr 24;10:409. doi: 10.3389/fphar.2019.00409

FIGURE 3.

FIGURE 3

Inhibitory effect of loganin on locomotor activity in normal mice. 5–240 min after administration of loganin (5, 20, 50 mg/kg, i.g.) or estazolam (0.15 mg/kg, i.g.), spontaneous locomotor activity was monitored. Data are presented as means ± SEM (n = 12). +P < 0.05, loganin 5 mg/kg, vs. the control group; XP < 0.05, loganin 20 mg/kg, vs. the control group; P < 0.05, ∗∗P < 0.01, loganin 50 mg/kg vs. the control group; #P < 0.05, ##P < 0.01, estazolam 0.15 mg/kg, vs. the control group (one-way ANOVA followed by Student-Newman-Keuls test).