Figure 1.

Pedigree of the family compiled with X-linked dominant inheritance. Square represents male and circle represents female. Filled symbol indicates affected. Dot symbol indicates deduced affected individual with medical history. A slash through a symbol indicates deceased individual. Arrow indicates the proband. The symbol “+” indicates a carrier of the variant. The symbol “–” indicates wild genotype. No symbol means the individual's genetic test is not available. The pedigree has been edited to maintain the confidentiality of family members.