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. 2019 Mar 30;46(2):193–210. doi: 10.1007/s10928-019-09629-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 7 — Variation of a percent error for k₁ and k₂ with the ratio of $Γ / δ$ b RMSE between the predicted and observed concentration with $Γ / δ$ . The root mean square error has units of concentration