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. 2019 Apr 24;9:308. doi: 10.3389/fonc.2019.00308

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Copyright © 2019 Rawal, Siddiqui, Hassan, Choudhary, Tripathi, Nain, Trehanpati and Kaur.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Epithelial mesenchymal transition in different hepatoma cells in presence of media alone or TGF-β. (A) Bar diagram showing average relative wound width at 24 h divided by that at 0 h in control transfected Huh7 (Ct-Huh7), HBx-Huh7, and Hep3B cells. (B,C) Chemotaxis and matrigel invasion transwell assays depicting migration of hepatoma cells from upper to lower chamber. (D) Relative mRNA expression of mesenchymal genes in hepatoma cells. Data is represented as mean ± SD (n = 3 each). *p < 0.05; **p < 0.01, ***p < 0.001.