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. 2019 Apr 24;10:256. doi: 10.3389/fendo.2019.00256

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Copyright © 2019 Baig, Parvaresh Rizi, Chia, Shabeer, Aung, Loh, Magkos, Vidal-Puig, Seet, Khoo and Toh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Postprandial change in urine F₂-IsoPs concentration corrected for urine creatinine concentration (F₂-IsoP/Cr ratio) from baseline to 6 h after high carbohydrate (HC), high-fat (HF), and high-protein (HP) meal ingestion in lean and obese individuals. Values are mean ± SEM and analyzed by using two-tailed t-tests between lean vs. obese subject after HC (−0.08 ± 0.23 vs. 0.18 ± 0.15, P = 0.35), HF (0.40 ± 0.09 vs. 0.18 ± 0.11, P = 0.14), and HP (0.10 ± 0.21 vs. 0.29 ± 0.25, P = 0.56) meals, and indicated with (^*) when significant (P < 0.05). Independent of diet, postprandial urinary F₂-IsoP/Cr significantly increased in obese, but not lean individuals.