Table 1.
Characteristics of 145 liver transplant recipients.
| Liver transplant recipients N = 145 | ||||||
|---|---|---|---|---|---|---|
| Total | Non-rejectors. N = 120 | Rejectors N = 17 | Subclinical rejectors N = 8 | P-value | ||
| Sex (male) | 105 (72.4%) | 89 (74.2%) | 12 (70.6%) | 4 (50%) | 0.35 | |
| Recipient age (years) | 56.5 ± 8.6 | 58.5 ± 8.5 | 51.0 ± 9.6 | 57.0 ± 7.9 | 0.74 | |
| Primary disease | Alcohol | 34 (23.5%) | 27 (22.5%) | 5 (29.4%) | 2 (25%) | 0.50 |
| HCV | 44 (30.3%) | 38 (31.7%) | 4 (23.5) | 2 (25%) | ||
| HCV + Alcohol | 9 (6.2%) | 8 (6.7%) | 1 (5.9%) | 0 | ||
| HBV | 10 (6.9%) | 10 (8.3%) | 0 | 0 | ||
| Autoimmune | 6 (4.1%) | 4 (3.3%) | 0 | 2 (25%) | ||
| PBC | 10 (6.9%) | 7 (5.8%) | 2 (11.8%) | 1 (12.5%) | ||
| PSC | 4 (2.8%) | 3 (2.5%) | 1 (5.9%) | 0 | ||
| Cryptogenic | 7 (4.8%) | 5 (4.2%) | 1 (5.9%) | 1 (12.5%) | ||
| NASH | 11 (7.6%) | 9 (7.5%) | 2 (11.8%) | 0 | ||
| Other | 10 (6.9%) | 9 (7.5%) | 1 (5.9%) | 0 | ||
| Hepatocellular carcinoma | 69 (47.6%) | 58 (47.9%) | 7 (42.8%) | 4 (50%) | 0.94 | |
| Donor age (years) | 58.5 ± 14.4 | 58.6 ± 15.5 | 53.0 ± 15.3 | 68.5 ± 8.4 | 0.22 | |
| Cold ischemia time (minutes) | 460.6 ± 146 | 443.5 ± 133.8 | 430 ± 112.2 | 515.0 ± 133.8 | 0.65 | |
| Type of donor | Living donor | 1 (0.7%) | 1 (0.8%) | 0 | 0 | 0.61 |
| DBD | 123 (84.8%) | 103 (85.8%) | 14 (82.4%) | 6 (75%) | ||
| DCD | 21 (14.5%) | 16 (13.4%) | 3 (17.6%) | 2 (25%) | ||
| Immunosuppressive regimen | TAC + PDN | 61 (42.1%) | 49 (40.8%) | 8 (47.1%) | 4 (50%) | 0.45 |
| TAC + MMF + PDN | 54 (37.2%) | 43 (35.8%) | 8 (47.1%) | 3 (37.5%) | ||
| CsA + PDN | 15 (10.3%) | 14 (11.7%) | 0 | 1 (12.5%) | ||
| CsA + MMF + PDN | 15 (10.3%) | 14 (11.7%) | 1 (5.8%) | 0 | ||
| Post-transplant infections | HCV | 8 (5.5%) | 8 (6.7%) | 0 | 0 | 0.59 |
| CMV | 41 (28.3%) | 34 (28.3%) | 4 (23.5%) | 3 (37.5%) | 0.62 | |
| Bacterial | 48 (33.1%) | 35 (29.2%) | 8 (47.1%) | 5 (62.5%) | 0.07 | |
Quantitative variables are displayed with median and standard deviation. Count variables are displayed raw and intragroup relative frequency. HCV, Hepatitis C Virus; HBV, Hepatitis B Virus; PBC, Primary Biliary Cholangitis; PSC, Primary Sclerosing Cholangitis; NASH, Non-Alcoholic Steatohepatitis; DBD, Donor after Brain Death; DCD, Donor after Cardiac Death; TAC, Tacrolimus; PDN, Prednisone; MMF, Mycophenolate Mofetil; CsA, Cyclosporine A; CMV, Cytomegalovirus.