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. 2019 Apr 24;6:45. doi: 10.3389/fcvm.2019.00045

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Copyright © 2019 Kambis, Shahshahan, Kar, Yadav and Mishra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cardiac-specific miR-133a prevents DM-induced lipid accumulation in the heart. Oil Red O staining of the heart cryosections. Representative left ventricle heart section of WT, Akita, Akita/miR-133aTg, and miR-133aTg mice (400× magnification). Quantification of red color in bar graph. Values are presented as mean ± SEM. One-way analysis of variance (ANOVA) followed by Tukey's test was used for statistical significance. Red color represents lipid deposition and light blue color represents nuclei. N = 4 per group. *P < 0.05; **P < 0.01.