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. 2019 Apr 24;10:691. doi: 10.3389/fmicb.2019.00691

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Copyright © 2019 Zhang, Li, Lv, Yan, Wang and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Predicted SRS1 (the positions 117–134) and SRS4 (the positions 305–314) of tested fungal CYP51 (S. cerevisiae, C. albicans, C. glabrata, C. tropicalis, C. krusei, C. dubliniensis, C. parapsilosis, A. fumigatus, and Cryptococcus neoformans). The sequences were from NCBI and CGD database and the consensus logos were generated by WebLogo (http://weblogo.threeplusone.com/create.cgi); (B) Location of SRS1(yellow) and SRS4 (blue) in C. albicans CYP51 (5v5z). HEME is shown in red. They are obtained from the published crystal data file from the PDB database, and then displayed by PyMOL Version 1.5.0.3.