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. 2019 Apr 24;7:236. doi: 10.3389/fchem.2019.00236

Figure 3.

Figure 3

The suppressive effect of 8i (A) and GSK2126458 (B) on the phosphorylation of Akt, S6 Ribosomal protein, and 4E-BP1 in PC3 cells following 3 h-treatment: The levels of phos-Akt (Ser473), phos-Akt (Thr308), phos-S6 ribosomal protein (Ser235/236), and phos-4E-BP1 (Thr37/46) in different groups were determined via Western blot assay. The bar chart represented the quantification of the bands in the Western blot with the results shown as mean ± SD (n = 3 biological replicates). **p < 0.01 vs. control (cells incubated without 8i or GSK2126458).