Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 24;10:864. doi: 10.3389/fmicb.2019.00864

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Hartmann, Piontkivska, Moreira and Silva Pereira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A) Schematic representation of the first steps in the sphingolipid biosynthetic pathway. (B) Expression levels of the genes mediating the first steps of sphingolipid biosynthesis after 4 h of exposure to dodecyltributylphosphonium chloride ([P₄₄₄₁₂]Cl, black bars) compared to the control (white bars). Axis y represents the fold-change relative to time-zero (^∗∗p < 0.01, ^∗∗∗p < 0.001). (C) Sphingoid bases accumulation profile after 4, 8, 12, and 24 h of exposure to [P₄₄₄₁₂]Cl. The peaks assigned to phytosphingosine, sphingosine and dihydrosphingosine were confirmed by their standards.