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Fractional Inhibitory Concentration Index (FICI) of sub-inhibitory manuka honey concentrations supplemented with one of three clinically relevant antibiotics; ciprofloxacin (A), ceftazidime (B) and tobramycin (C). The interaction between manuka honey and antibiotics were interpreted as ’synergistic (FICI < 0.5), “antagonistic” (FICI > 4.0), and “no interaction” (FICI > 0.5–4.0).
