Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 24;10:359. doi: 10.3389/fgene.2019.00359

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Norris, Rishishwar, Wang, Conley, Chande, Dabrowski, Valderrama-Aguirre and Jordan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Approach used to measure assortative mating on local ancestry. (A) Local ancestry is assigned for specific haplotypes across the genome: African (blue), European (orange), and Native American (red). (B) Within individual genomes, genes are characterized as homozygous or heterozygous for local ancestry. For any given population, at each gene locus, the assortative mating index (AMI) is computed from the observed and expected counts of homozygous and heterozygous gene pairs. (C) Data from genome-wide association studies (GWAS) are used to evaluate polygenic phenotypes. (D) Meta-analysis of AMI values is used to evaluate the significance of ancestry-based assortative mating for polygenic phenotypes.