Table 1.
No sepsis n = 46* | Sepsis n = 8 | p Value | |
---|---|---|---|
Gestational age | 29.6 ± 3.2 | 28.1 ± 3.1 | ns |
Male:Female ratio | 29:17 | 4:4 | ns |
Age at sample collection (days) | 1–30 | 1–20 | ns |
Number of endotracheal aspirate (ETA) samples | 91 | 21 | |
Surfactant PC (%)§ | 71.7 (61.9–81.0)† | 69.8 (57.6–77.4) | |
OR 0.964, 95% CI 0.909–1.023‡ | ns | ||
Mono‐/Di‐unsaturated PC (%)¶ | 18.1 (14.6–21.8) | 19.6 (16.7–25.3) | |
OR 1.096, 95% CI 1.00–1.203 | 0.05 | ||
Polyunsaturated PC (%)** | 4.8 (2.7–7.1) | 2.4 (1.3–3.5) | |
OR 0.721, 95% CI 0.565–0.920 | <0.01 |
GA, Gestational age; M:F, Male: female.
Analysis studied: (i) surfactant PC, (ii) mono‐unsaturated and di‐unsaturated PC, (iii) polyunsaturated PC. All 46 neonates with no sepsis versus eight neonates with sepsis.
n, number of neonates.
Median [interquartile range (IQR)].
Generalised linear model adjusted for repeated sampling with neonates and GA and presented as OR, odds ratio, CI, confidence interval.
Surfactant PC: PC(14:0/16:0); PC(16:0A/16:1); PC(14:0/18:2); PC(16:0/16:1); PC[16:0/16:0 (DPPC)].
Mono‐unsaturated/di‐unsaturated PC: PC(16:0/18:2); PC(16:0/18:1); PC(18:1/18:2); PC(18:0/18:2).
Polyunsaturated PC: PC(16:0/20:4); PC(16:0/22:6); PC(18:1/20:4); PC(18:0/20:4).