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. 2019 Jan 8;108(5):870–876. doi: 10.1111/apa.14630

Table 1.

Baseline characteristics of the 54 neonates included in the study without (46) and with (8) sepsis

No sepsis n = 46* Sepsis n = 8 p Value
Gestational age 29.6 ± 3.2 28.1 ± 3.1 ns
Male:Female ratio 29:17 4:4 ns
Age at sample collection (days) 1–30 1–20 ns
Number of endotracheal aspirate (ETA) samples 91 21
Surfactant PC (%)§ 71.7 (61.9–81.0) 69.8 (57.6–77.4)
OR 0.964, 95% CI 0.909–1.023 ns
Mono‐/Di‐unsaturated PC (%) 18.1 (14.6–21.8) 19.6 (16.7–25.3)
OR 1.096, 95% CI 1.00–1.203 0.05
Polyunsaturated PC (%)** 4.8 (2.7–7.1) 2.4 (1.3–3.5)
OR 0.721, 95% CI 0.565–0.920 <0.01

GA, Gestational age; M:F, Male: female.

Analysis studied: (i) surfactant PC, (ii) mono‐unsaturated and di‐unsaturated PC, (iii) polyunsaturated PC. All 46 neonates with no sepsis versus eight neonates with sepsis.

*

n, number of neonates.

Median [interquartile range (IQR)].

Generalised linear model adjusted for repeated sampling with neonates and GA and presented as OR, odds ratio, CI, confidence interval.

§

Surfactant PC: PC(14:0/16:0); PC(16:0A/16:1); PC(14:0/18:2); PC(16:0/16:1); PC[16:0/16:0 (DPPC)].

Mono‐unsaturated/di‐unsaturated PC: PC(16:0/18:2); PC(16:0/18:1); PC(18:1/18:2); PC(18:0/18:2).

**

Polyunsaturated PC: PC(16:0/20:4); PC(16:0/22:6); PC(18:1/20:4); PC(18:0/20:4).