Table 5.

Random‐effects meta‐analysis results for summary effect size (standardized mean difference [SMD]), 95% confidence intervals (CIs), and heterogeneity standard deviation for the two sources of evidence and for various BIP and IMP scenarios. Results from the sensitivity analyses are based on fourteen studies

	Scenarios	SMD (95% CI)
Neutral Scenarios
	Complete case analysis [1]	−0.28 (−0.51,−0.04)
	LOCF analysis [2]	−0.13 (−0.20, −0.05)
N1	${\delta }_{\mathit{ij}}^{\mathrm{imp}}\sim N\left(0,3^2\right)$, ${\delta }_{\mathit{ij}}^{\mathrm{\text{miss}}}\sim N\left(0,3^2\right)$	−0.11 (−0.21, −0.02)
N2	${\delta }_{\mathit{ij}}^{\mathrm{imp}}\sim N\left(0,5^2\right)$, ${\delta }_{\mathit{ij}}^{\mathrm{\text{miss}}}\sim N\left(0,5^2\right)$	−0.12 (−0.24, −0.00)
N3	${\delta }_{\mathit{ij}}^{\mathrm{imp}}\sim N\left(0,{10}^2\right)$, ${\delta }_{\mathit{ij}}^{\mathrm{\text{miss}}}\sim N\left(0,{10}^2\right)$	−0.13 (−0.33, 0.07)
N4	${\delta }_{\mathit{ij}}^{\mathrm{imp}}\sim N\left(-5,2^2\right)$, ${\delta }_{\mathit{ij}}^{\mathrm{\text{miss}}}\sim N\left(5,2^2\right)$	−0.09 (−0.17, −0.01)
N5	${\delta }_{\mathit{ij}}^{\mathrm{imp}}\sim N\left(-10,5^2\right)$, ${\delta }_{\mathit{ij}}^{\mathrm{\text{miss}}}\sim N\left(10,5^2\right)$	−0.10 (−0.22, 0.03)
Scenarios That Favor Fluoxetine
F1	${\delta }_{\mathit{iT}}^{\mathrm{imp}}\sim N\left(-5,2^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{imp}}\sim N\left(-10,2^2\right)$, ${\delta }_{\mathit{iT}}^{\mathrm{\text{miss}}}\sim N\left(5,2^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{\text{miss}}}\sim N\left(10,2^2\right)$	0.00 (−0.09, 0.08)
F2	${\delta }_{\mathit{iT}}^{\mathrm{imp}}=0$, ${\delta }_{\mathit{iC}}^{\mathrm{imp}}\sim N\left(-5,2^2\right)$, ${\delta }_{\mathit{iT}}^{\mathrm{\text{miss}}}=0$, ${\delta }_{\mathit{iC}}^{\mathrm{\text{miss}}}\sim N\left(5,2^2\right)$	−0.01 (−0.08, 0.07)
F3	${\delta }_{\mathit{iT}}^{\mathrm{imp}}\sim N\left(-5,5^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{imp}}\sim N\left(-10,5^2\right)$, ${\delta }_{\mathit{iT}}^{\mathrm{\text{miss}}}\sim N\left(5,5^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{\text{miss}}}\sim N\left(10,5^2\right)$	−0.03 (−0.15, 0.10)
Scenarios That Favor Venlafaxine
V1	${\delta }_{\mathit{iT}}^{\mathrm{imp}}\sim N\left(-5,2^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{imp}}=0$, ${\delta }_{\mathit{iT}}^{\mathrm{\text{miss}}}\sim N\left(5,2^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{\text{miss}}}=0$	−0.19 (−0.28, −0.11)
V2	${\delta }_{\mathit{iT}}^{\mathrm{imp}}\sim N\left(-10,2^2\right),$ ${\delta }_{\mathit{iC}}^{\mathrm{imp}}\sim N\left(-5,2^2\right)$, ${\delta }_{\mathit{iT}}^{\mathrm{\text{miss}}}\sim N\left(10,2^2\right),$ ${\delta }_{\mathit{iC}}^{\mathrm{\text{miss}}}\sim N\left(5,2^2\right)$	−0.17 (−0.25, −0.08)
V3	${\delta }_{\mathit{iT}}^{\mathrm{imp}}\sim N\left(-10,5^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{imp}}\sim N\left(-5,5^2\right)$, ${\delta }_{\mathit{iT}}^{\mathrm{\text{miss}}}\sim N\left(10,5^2\right)$, ${\delta }_{\mathit{iC}}^{\mathrm{\text{miss}}}\sim N\left(5,5^2\right)$	−0.18 (−0.31, −0.06)

^[1] Complete case analysis is based on four studies.

^[2] Last observation carried forward (LOCF) analysis is based on thirteen studies.