The reconstructed MWF-maps (right panel) are compared for competing processing approaches, namely: the PM approach, our 2D multi-slice spatial regularization approach, the current approach for simulated MWF-map (left panel) at different SNR (10000, 500, 200, 100). At high SNR of 10000, MWF-map reconstructed using either of methods were very close to the simulated truth. At lower SNR (200, 100), the Prasloski’s method (PM) led to large intra-structural variabilities. At SNR ≤ 200, the current approach reconstruct more faithfully than our earlier 2D- multi slice approach. Also, notice that MWF-reconstructions using the proposed approach are closer to the simulated truth.