Table 4.
Factors associated with pre‐treatment IgG1, IgG4 and IgE detectable responses against Schistosoma mansoni schistosomula antigens
| Antigen | Factor | Level | IgG1 | IgG4 | IgE | |||
|---|---|---|---|---|---|---|---|---|
| Adjusteda OR (95% CI) | P‐value | Adjusteda OR (95% CI) | P‐value | Adjusteda OR (95% CI) | P‐value | |||
| SmKK7 | Sex | Female | 1 | 0.009 | 1 | 0.143 | 1 | 0.625 |
| Male | 2.09 (1.20‐3.65) | 1.62 (0.85‐3.07) | 0.86 (0.48‐1.56) | |||||
| Age (years) | 6 to 9 | 1 | 0.739 | 1 | 0.019 | 1 | 0.943 | |
| 10 to 13 | 1.31 (0.66‐2.60) | 1.96 (0.92‐4.18) | 0.88 (0.42‐1.84) | |||||
| 14+ | 1.15 (0.60‐2.21) | 0.66 (0.28‐1.53) | 0.96 (0.60‐2.21) | |||||
| SmLy6a | Sex | Female | 1 | 0.006 | 1 | 0.073 | 1 | 0.549 |
| Male | 3.13 (1.39‐7.02) | 4.37 (0.87‐21.89) | 1.5 (0.39‐5.91) | |||||
| Age (years) | 6 to 9 | 1 | 0.441 | 1 | 0.380 | 1 | 0.716 | |
| 10 to 13 | 0.93 (0.37‐2.28) | 1.18 (0.27‐5.04) | 0.51 (0.09‐2.85) | |||||
| 14+ | 1.15 (0.21‐1.45) | 0.25 (0.03‐2.31) | 0.65 (0.13‐3.08) | |||||
| SmLy6b | Sex | Female | 1 | 0.304 | 1 | 0.713 | 1 | 0.438 |
| Male | 1.39 (0.74‐2.59) | 1.17 (0.51‐2.67) | 0.81 (0.48‐1.38) | |||||
| Age (years) | 6 to 9 | 1 | 0.069 | 1 | 0.001 | 1 | 0.082 | |
| 10 to 13 | 2.47 (1.08‐5.61) | 3.60 (1.33‐9.76) | 1.98 (1.02‐3.83) | |||||
| 14+ | 1.10 (0.54‐2.20) | 0.54 (0.15‐2.01) | 1.12 (0.59‐2.12) | |||||
| SmTSP7 | Sex | Female | 1 | 0.798 | 1 | 0.117 | 1 | 0.186 |
| Male | 1.07 (0.63‐1.81) | 2.46 (0.79‐7.56) | 2.19 (0.68‐7.00) | |||||
| Age (years) | 6 to 9 | 1 | 0.309 | 1 | 0.224 | 1 | 0.969 | |
| 10 to 13 | 1.58 (0.82‐3.06) | 0.93 (0.29‐2.96) | 1.08 (0.26‐4.58) | |||||
| 14+ | 1.54 (0.82‐2.92) | 0.25 (0.05‐1.28) | 1.19 (0.30‐4.71) | |||||
OR, odds ratio.
a
Adjusted for either sex or age.