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. 2019 Apr 30;11:26. doi: 10.1186/s13073-019-0640-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The effect of MS risk SNP genotype on expression of proximal genes in whole blood and LCLs. The GTEx eQTL dataset was first filtered for MS risk SNPs, and SNP:gene pairs were then plotted for effect of genotype (restricted to the genes closest to the MS risk SNPs—the proximal genes). SNP:gene pairs that were more strongly associated with expression in LCLs (coloured blue) and those with a different risk allele effect in LCLs compared to whole blood, more significant in LCLs (red) or opposite slope in LCLs(green) were identified as LCLeQTL*