Table 3.
Evaluation of NBI pattern III-IV and pattern IV alone as a diagnostic test for OSCC/Cis/HGD, with and without OLP patients
| Diagnostic test | Pattern III-IV (95% CI) | Pattern IV (95% CI) |
|---|---|---|
| Sensitivity | ||
| With OLP patients | 96.2% (80.4–99.9%) | 84.6% (65.1–95.6% |
| Without OLP patients | 96.2% (80.4–99.9%) | 84.6% (65.1 95.6%) |
| Specificity | ||
| With OLP patients | 71.3% (60.0–80.8%) | 97.5% (91.2–99.7%) |
| Without OLP patients | 80.0% (66.3–89.9%) | 96.0% (86.3–99.5%) |
| PLR | ||
| With OLP patients | 3.34 (2.35–4.76) | 33.85 (8.53–134.30) |
| Without OLP patients | 4.81 (2.75–8.41) | 21.15 (5.39–83.06) |
| NLR | ||
| With OLP patients | 0.05 (0.01–0.37) | 0.16 (0.06–0.39) |
| Without OLP patients | 0.05 (0.01–0.33) | 0.16 (0.06–0.40) |
| PPV | ||
| With OLP patients | 52.1% (43.3–60.7%) | 91.7% (73.5–97.7% |
| Without OLP patients | 71.4% (58.8–81.4%) | 91.7% (73.7–97.7%) |
| NPV | ||
| With OLP patients | 98.3% (89.2–99.7% | 95.1% (88.8–97.9% |
| Without OLP patients | 97.6% (85.3–99.6%) | 92.3% (82.9–96.7%) |
| Accuracy | ||
| With OLP patients | 77.4% (68.2–84.9%) | 94.3% (88.1–97.9%) |
| Without OLP patients | 85.5% (75.6–92.5%) | 92.1% (83.6–97.1%) |
PLR positive likelihood ratio, NLR negative likelihood ratio, PPV positive predictive value, NPV negative predictive value, CI confidence interval