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. 2019 Apr 29;15:1745506519844044. doi: 10.1177/1745506519844044

Table 9.

Characteristics of the studies included in the evaluation for motor development in children.

First author’s name Sociodemographic data:
1. Country
2. Maternal mean age
3. Gender of newborns
Sample size Design:
1. Study design
2. Time of follow-up
3. Number of groups
4. Description of groups
Tool used to assess PPD Prevalence of PPD Outcomes Main results
Ali94 Pakistan
Mean age: 26.3 years
Female babies: 48.8%
420 Cohort study
30 months
Two groups:
- PPD
- No PPD
AKUADS 1 month: 4.8%
2 months: 4.7%
6 months: 5.7%
12 months: 9.2%
18 months: 2.7%
24 months: 6.1%
Delayed gross motor, fine motor, emotional, cognitive, and language development At the 2- and 6-month follow-ups, there was no significant impact of maternal depression on children’s gross motor development. However, there was an approximately three-fold higher impact at the 12-month follow-up (adjusted OR = 2.8, 95% CI = 1.2, 6.6). At the 2-, 6-, and 12-month follow-ups, there was no significant impact of maternal depression on children’s fine motor development. At the 18-month follow-up, there was a significant impact; children of depressed mothers had a four times higher risk (adjusted OR = 4.0, 95% CI = 1.4, 11.3).
Chen141 Taiwan
Mean age: 26.6 ± 4.2 years
Female babies: 42.6%
NB: immigrant mothers
60 Cross-sectional study
Two groups:
- PPD
- No PPD
EPDS
(Depressed = EPDS ⩾ 10)
31.1% Child development (global score for cognitive, language, motor, self-regulation, and social development); quality of the home environment Maternal depressive symptoms had a direct and negative effect on the quality of the home environment (−0.32, p < 0.05). Maternal depressive symptoms did not have a direct effect on child development (0.05, p > 0.05). The quality of the home environment had a significant and positive effect on child development (0.55, p < 0.001).
Koutra95 Crete
Mean age: 30.09 ± 4.53 years
Female babies: 45.5%
470 Cohort study
18 months
Two groups:
- PPD
- No PPD
EPDS
(Depressed = EPDS ⩾ 13)
Not given Fine motor, gross motor, cognitive, and social-emotional development; receptive and expressive communication High levels of maternal PPD (EPDS score ⩾ 13) were associated with 5-unit decrease in the fine motor development scale score at 18 months of age.
Nasreen97 Bangladesh
Mean age: 24.2 ± 6.7 years
Female babies: 50.7%
652 Cohort study
1 year
Four groups:
- No depression
- Pregnancy only
- Pregnancy and postpartum
- Postpartum only
EPDS
(Depressed = EPDS ⩾ 10)
14.1% at 2–3 months
31.7% at 6–8 months
Infant growth (underweight at 6–8 months, stunting at 6–8 months); infant motor development Maternal depressive symptoms at 2–3 months postpartum predicted impaired infant motor development at 6–8 months.
Piteo103 Australia
Age: not given
Female babies: 53%
360 Cohort study
18 months
Two groups:
- PPD
- No PPD
EPDS
(Depressed = EPDS ⩾ 12)
19% Motor, cognitive, and language development In the first 6 months postpartum, there were no significant associations between maternal depression and motor development after controlling for infant prematurity, breastfeeding status, and socioeconomic level. There were no significant differences between maternal depression groups for motor development at 18 months based on unadjusted analyses. However, the home environment was a significant predictor of language development.
Sutter-Dallay107 France
Mean age: 29.6 ± 4.2 years
Female babies: 47.8%
515 Cohort study
2 years
Two groups:
- PPD
- No PPD
EPDS
(Depressed = EPDS > 12)
6 weeks: 4.7%
3 months: 4.5%
6 months: 4.3%
12 months: 3.7%
18 months: 5.8%
24 months: 4.3%
Psychomotor Developmental Index; Mental Developmental Index No association was found between PND 6 weeks after delivery and the child’s motor performance over the follow-up period. No association was found between EPDS scores and motor scores (B = 0.60, p = 0.24).
Wang66 Taiwan
Age (years):
 Depressed: 28.34 ± 5.52
 Nondepressed: 29.45 ± 4.13
Female babies: 55.0%
60 Cohort study
1 year
Two groups:
- PPD
- No PPD
BDI-II 48.3% Gross motor, fine motor, expressive language, comprehension-conceptual, situational help, self-help, personal-social, and general development No significant difference was found between the infant development variables in the two groups (gross motor development: p = 0.514; fine motor development: p = 0.514).

PPD: postpartum depression; AKUADS: Aga Khan University Anxiety and Depression Scale; EPDS: Edinburgh Postnatal Depression Scale; BDI-II: Beck Depression Inventory-II; CI: confidence interval; OR: odds ratio; PND: postnatal depression.