Table 1.
Clinical and demographic characteristics of the study population
| Clinical Characteristics | Extrapulmonary (N = 12) |
Pulmonary TB (N = 20) |
Latent TB Infection (N = 20) |
Uninfected (N = 21) |
P-value |
|---|---|---|---|---|---|
| Age in years | 41 (31, 61) | 58 (44, 66) | 44 (32, 54) | 49 (32, 53) | 0.06 |
| Female sex (%) | 5 (42) | 6 (30) | 15 (75) | 12 (57) | 0.03 |
| Black race (%) | 3 (25) | 3 (15) | 12 (60) | 8 (38) | < 0.01 |
| Hispanic ethnicity (%) | 3 (25) | 2 (10) | 3 (15) | 0 (0) | 0.10 |
| Foreign born (%) | 8 (67) | 2 (10) | 4 (20) | 1 (5) | < 0.01 |
| Alcohol use (4 or more times/week) | 3 (25) | 12 (60) | 7 (35) | 11 (52) | 0.19 |
| Tobacco use (≥10 cigarettes/day) | 2 (17) | 12 (60) | 5 (25) | 2 (10) | < 0.01 |
| Months from treatment completion to blood draw | 30.2 (10.7, 68.7) | 22.3 (8.7, 32.4) | 12 (12, 12)a | N/A | 0.35 |
| WBC (per mm3) | 7.4 (5.5, 8.4) | 7.1 (5.4, 9.8) | 6.7 (5.7, 8.8) | 7.8 (5.9, 9.6) | 0.80 |
| Monocytes (per mm3) | 6.5 (6.0, 8.5) | 6.0 (5.0, 8.0) | 6.0 (5.6, 7.0) | 6.0 (5.0, 7.6) | 0.79 |
| CD4+ lymphocytes (per mm3) | 1021 (713, 1263) | 994 (573, 1135) | 1152 (990, 1447) | 1285 (948, 1432) | 0.08 |
| CD8+ lymphocytes (per mm3) | 562 (375, 647) | 583 (311, 761) | 622 (461, 856) | 540 (362, 635) | 0.68 |
Values are presented as number (%) for categorical variables and median (inter-quartile range) for continuous variables
P-values are from the Fisher’s Exact test for differences in proportions for categorical variables, and the Kruskall-Wallis test for differences in the distribution of continuous variables
aThree participants with LTBI were documented to have completed treatment